Molecular Biology of Cancer
Mechanisms, Targets, and Therapeutics
Price: 1200.00 INR
ISBN:
9780198728696
Publication date:
20/06/2014
Paperback
360 pages
240.0x184.0mm
Price: 1200.00 INR
ISBN:
9780198728696
Publication date:
20/06/2014
Paperback
360 pages
240.0x184.0mm
Third Edition
Lauren Pecorino
The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents.
Suitable for: Advanced undergraduates and beginning graduates on biochemistry, molecular biology, and biomedical-related programmes of study.
Rights: OUP UK (Indian Territory)
Third Edition
Lauren Pecorino
Description
The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents. Opening with an overview of the key hallmarks of cancer as a disease state, the book then leads us through the principal processes that become altered in cancer cells, and explains how the failure of these processes can lead to the onset of cancer. Uniquely, within each chapter, students are shown how this molecular knowledge is being applied to develop new targeted therapeutic strategies.
Third Edition
Lauren Pecorino
Table of contents
Chapter 1. Introduction
Chapter 2. DNA structure and stability. mutations versus repair
Chapter 3. Regulation of gene expression
Chapter 4. Growth factor signaling and oncogenes
Chapter 5. The cell cycle
Chapter 6. Growth inhibition and tumour suppressor genes
Chapter 7. Apoptosis
Chapter 8. Stem cells and differentiation
Chapter 9. Metastasis
Chapter 10. The immune system, infections, and inflammation
Chapter 11. Nutrients, hormones, and gene interactions
Chapter 12. The cancer industry. drug development, pharmacogenomics, and clinical trial design
Chapter 13. Cancer in the future. focus on cancer vaccines and technology
Third Edition
Lauren Pecorino
Features
- Increased depth in coverage of cancer stem cell biology, metastasis, and micro RNAs
- Additional background information and enhanced explanation of immunology
- New topics covered, including evidence for the role of chromothripsis in carcinogenesis and the therapeutic potential of gene signatures
Third Edition
Lauren Pecorino
Description
The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents. Opening with an overview of the key hallmarks of cancer as a disease state, the book then leads us through the principal processes that become altered in cancer cells, and explains how the failure of these processes can lead to the onset of cancer. Uniquely, within each chapter, students are shown how this molecular knowledge is being applied to develop new targeted therapeutic strategies.
Read MoreTable of contents
Chapter 1. Introduction
Chapter 2. DNA structure and stability. mutations versus repair
Chapter 3. Regulation of gene expression
Chapter 4. Growth factor signaling and oncogenes
Chapter 5. The cell cycle
Chapter 6. Growth inhibition and tumour suppressor genes
Chapter 7. Apoptosis
Chapter 8. Stem cells and differentiation
Chapter 9. Metastasis
Chapter 10. The immune system, infections, and inflammation
Chapter 11. Nutrients, hormones, and gene interactions
Chapter 12. The cancer industry. drug development, pharmacogenomics, and clinical trial design
Chapter 13. Cancer in the future. focus on cancer vaccines and technology